Chemical Composition Characterization and Potential Medicinal Utilization of Extracts and Pyrolysis Products from Carpinus cordata Wood

Abstract

Woody plants represent a valuable source of bioactive compounds for medicine. In this study, Carpinus cordata wood was extracted with different solvents. The extracts were analyzed using Fourier transform infrared (FTIR), thermogravimetric analysis (TGA), gas chromatography-mass spectrometry (GC-MS), pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS), and thermal desorption - gas chromatography - mass spectrometry (TD-GC-MS). The results revealed a diverse array of compounds, including aromatic and aliphatic hydrocarbons, alkanes, aldehydes, ketones, carboxylic acids, and esters. These chemical constituents demonstrate significant potential as feedstocks for bio-oils and novel biomaterials in industrial and agricultural sectors. Furthermore, specific bioactive molecules with potential anti-inflammatory, anticancer, and anti-HIV properties were identified, underlining their promise for pharmaceutical and biomedical agents. Live/dead staining results of ethanol extracts of C. cordata wood exhibited significant cytotoxicity against the human chronic myeloid leukemia cell line K-562, indicating the presence of potent anti-cancer constituents. Overall, the multifaceted potential of C. cordata wood was shown to be a source of both bioactive extracts for medicine and valuable chemicals through thermochemical conversion.